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A Unique Three-Way Variant Philadelphia Chromosome t(6;9;22)(p21.3;q34;q11.2) in a Newly Diagnosed Patient with Chronic Myeloid Leukemia Responded to Flumatinib

BACKGROUND: Chronic myeloid leukaemia (CML) is a clonal malignant disorder of a pluripotent hematopoetic stem cell characterized by the presence of Philadelphia (Ph) chromosome in more than 90% of patients. However, about 5–10% of CML patients show a variant Ph translocation, involving one or more c...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Zhang, Junling, Yang, Na, Tan, Ningping, Meng, Di, Zhang, Fei, Qi, Yuyang, Wu, Guangqi, Li, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509008/
https://www.ncbi.nlm.nih.gov/pubmed/36164408
http://dx.doi.org/10.2147/OTT.S377342