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Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma
BACKGROUND: The hepatitis B virus X (HBx) protein plays a critical role in the initiation and progression of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). In the early stage of the disease, HBx facilitates tumor onset by inactivating the tumor suppressor p53. The p53-encoding ge...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509107/ https://www.ncbi.nlm.nih.gov/pubmed/35950770 http://dx.doi.org/10.1097/CM9.0000000000002283 |