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Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma

BACKGROUND: The hepatitis B virus X (HBx) protein plays a critical role in the initiation and progression of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). In the early stage of the disease, HBx facilitates tumor onset by inactivating the tumor suppressor p53. The p53-encoding ge...

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Detalles Bibliográficos
Autores principales: Xie, Bangxiang, Hao, Qian, Zhou, Xiang, Chen, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509107/
https://www.ncbi.nlm.nih.gov/pubmed/35950770
http://dx.doi.org/10.1097/CM9.0000000000002283

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