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Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics

The primary objective of this study was to develop and validate an efficient and accurate ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach as a means to detect tropifexor plasma concentrations in beagle dogs and to study its pharmacokinetic profile in beagle dog...

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Detalles Bibliográficos
Autores principales: Su, Yan-Ding, Wei, Xin-Yi, Su, Xiao-Hang, Woshur, Ghulam, Geng, Xiao-Nan, Qiu, Xiang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509244/
https://www.ncbi.nlm.nih.gov/pubmed/36164482
http://dx.doi.org/10.1155/2022/2823214