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Identification of potential modulators of IFITM3 by in-silico modeling and virtual screening
IFITM3 is a transmembrane protein that confers innate immunity. It has been established to restrict entry of multiple viruses. Overexpression of IFITM3 has been shown to be associated with multiple cancers, implying IFITM3 to be good therapeutic target. The regulation of IFITM3 activity is mediated...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509314/ https://www.ncbi.nlm.nih.gov/pubmed/36153346 http://dx.doi.org/10.1038/s41598-022-20259-8 |