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Identification of potential modulators of IFITM3 by in-silico modeling and virtual screening

IFITM3 is a transmembrane protein that confers innate immunity. It has been established to restrict entry of multiple viruses. Overexpression of IFITM3 has been shown to be associated with multiple cancers, implying IFITM3 to be good therapeutic target. The regulation of IFITM3 activity is mediated...

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Detalles Bibliográficos
Autores principales: Tiwari, Vikas, Viswanath, Shruthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509314/
https://www.ncbi.nlm.nih.gov/pubmed/36153346
http://dx.doi.org/10.1038/s41598-022-20259-8