Dithranol as novel co-adjuvant for non-invasive dermal vaccination

Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to boost vaccination efficacy (Dithranol/IMQ-based transcutane...

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Detalles Bibliográficos
Autores principales: Sohl, Julian, Hartmann, Ann-Kathrin, Hahlbrock, Jennifer, Bartneck, Joschka, Stassen, Michael, Klein, Matthias, Bros, Matthias, Grabbe, Stephan, Marini, Federico, Woods, Kevin, Guezguez, Borhane, Mack, Matthias, Schild, Hansjörg, Muth, Sabine, Melchior, Felix, Probst, Hans Christian, Langguth, Peter, Radsak, Markus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509335/
https://www.ncbi.nlm.nih.gov/pubmed/36153349
http://dx.doi.org/10.1038/s41541-022-00530-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509335/
https://www.ncbi.nlm.nih.gov/pubmed/36153349
http://dx.doi.org/10.1038/s41541-022-00530-9

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