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A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases
Sarcomas include cancer stem cells, but how these cells contribute to local and metastatic relapse is largely unknown. We previously showed the pro-tumor functions of calpain-6 in sarcoma stem cells. Here, we use an osteosarcoma cell model, osteosarcoma tissues and transcriptomic data from human tum...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509353/ https://www.ncbi.nlm.nih.gov/pubmed/36153320 http://dx.doi.org/10.1038/s41419-022-05244-3 |