A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases

Sarcomas include cancer stem cells, but how these cells contribute to local and metastatic relapse is largely unknown. We previously showed the pro-tumor functions of calpain-6 in sarcoma stem cells. Here, we use an osteosarcoma cell model, osteosarcoma tissues and transcriptomic data from human tum...

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Detalles Bibliográficos
Autores principales: Tchicaya-Bouanga, Joëlle, Hung, Yu-Jen, Schwartz, Jean-Marc, Yoon, Diane Ji Yun, Chotard, Emilie, Marty, Clarice, Odri, Guillaume Anthony, de Pinieux, Gonzague, Cohen-Solal, Martine, Modrowski, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509353/
https://www.ncbi.nlm.nih.gov/pubmed/36153320
http://dx.doi.org/10.1038/s41419-022-05244-3

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