Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway

Melatonin (MT), a neurohormone with immunomodulatory properties, is one of the metabolites produced in the brain from tryptophan (TRP) that has already strong links with the neuropathogenesis of Multiple sclerosis (MS). However, the exact molecular mechanisms behind that are not fully understood. Th...

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Detalles Bibliográficos
Autores principales: Jand, Yahya, Ghahremani, Mohammad Hossein, Ghanbari, Amir, Ejtemaei-Mehr, Shahram, Guillemin, Gilles J., Ghazi-Khansari, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509376/
https://www.ncbi.nlm.nih.gov/pubmed/36153399
http://dx.doi.org/10.1038/s41598-022-20164-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509376/
https://www.ncbi.nlm.nih.gov/pubmed/36153399
http://dx.doi.org/10.1038/s41598-022-20164-0

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