Human centromere repositioning activates transcription and opens chromatin fibre structure

Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres we...

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Detalles Bibliográficos
Autores principales: Naughton, Catherine, Huidobro, Covadonga, Catacchio, Claudia R., Buckle, Adam, Grimes, Graeme R., Nozawa, Ryu-Suke, Purgato, Stefania, Rocchi, Mariano, Gilbert, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509383/
https://www.ncbi.nlm.nih.gov/pubmed/36153345
http://dx.doi.org/10.1038/s41467-022-33426-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509383/
https://www.ncbi.nlm.nih.gov/pubmed/36153345
http://dx.doi.org/10.1038/s41467-022-33426-2

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