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For whom the bell tolls: psychopathological and neurobiological correlates of a DNA methylation index of time-to-death

Psychopathology is a risk factor for accelerated biological aging and early mortality. We examined associations between broad underlying dimensions of psychopathology (reflecting internalizing and externalizing psychiatric symptoms), PTSD, and age-adjusted GrimAge (“GrimAge residuals”), a DNA methyl...

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Detalles Bibliográficos
Autores principales: Hawn, Sage E., Zhao, Xiang, Sullivan, Danielle R., Logue, Mark, Fein-Schaffer, Dana, Milberg, William, McGlinchey, Regina, Miller, Mark W., Wolf, Erika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509393/
https://www.ncbi.nlm.nih.gov/pubmed/36153327
http://dx.doi.org/10.1038/s41398-022-02164-w