Cross-talk between enhancers, structural elements and activating transcription factors maintains the 3D architecture and expression of the CFTR gene

Robust protocols to examine 3D chromatin structure have greatly advanced knowledge of gene regulatory mechanisms. Here we focus on the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which provides a paradigm for validating models of gene regulation built upon genome-wide analysis....

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Detalles Bibliográficos
Autores principales: Yin, Shiyi, Mazumdar, Monali Nandy, Paranjapye, Alekh, Harris, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509493/
https://www.ncbi.nlm.nih.gov/pubmed/35346781
http://dx.doi.org/10.1016/j.ygeno.2022.110350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509493/
https://www.ncbi.nlm.nih.gov/pubmed/35346781
http://dx.doi.org/10.1016/j.ygeno.2022.110350

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