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Tumor-derived exosomal HOTAIRM1 regulates SPON2 in CAFs to promote progression of lung adenocarcinoma

OBJECTIVE: SPON2 is one of the extracellular matrix proteins, which is closely related to the progression of a variety of tumors including non-small cell lung cancer (NSCLC), but its upstream regulation mechanism remains unclear. Our research aims to find the specific regulatory pathway of SPON2 by...

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Detalles Bibliográficos
Autores principales: Chen, Zhipeng, Bian, Chengyu, Huang, Jingjing, Li, Xiang, Chen, Liang, Xie, Xueying, Xia, Yang, Yin, Rong, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509512/
https://www.ncbi.nlm.nih.gov/pubmed/36153414
http://dx.doi.org/10.1007/s12672-022-00553-7