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Combined Risk Assessment of Food-derived Coumarin with in Silico Approaches

Hepatotoxicity associated with food-derived coumarin occurs occasionally in humans. We have, herein, assessed the data of existing clinical and nonclinical studies as well as those of in silico models for humans in order to shed more light on this association. The average intakes of food-derived cou...

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Detalles Bibliográficos
Autores principales: Yamada, Takashi, Katsutani, Naruo, Maruyama, Taeko, Kawamura, Tomoko, Yamazaki, Hiroshi, Murayama, Norie, Tong, Weida, Yamazoe, Yasushi, Hirose, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Food Safety Commission, Cabinet Office, Government of Japan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509535/
https://www.ncbi.nlm.nih.gov/pubmed/36237397
http://dx.doi.org/10.14252/foodsafetyfscj.D-21-00015