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Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

BACKGROUND: Ultrasound-targeted microbubble destruction (UTMD) technology is a new drug and gene delivery strategy. This study investigates novel ultrasound (US) sensitive siRNA-loaded nanobubbles (siRNA-NBs) to explore the relationship between PDLIM5 mediated autophagy and drug resistance developme...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Lv, Wenhao, Li, Hui, Dong, Tiantian, Wu, Hao, Su, Chunhong, Shu, Hong, Nie, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509593/
https://www.ncbi.nlm.nih.gov/pubmed/36154921
http://dx.doi.org/10.1186/s12935-022-02718-4