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Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

BACKGROUND: Ultrasound-targeted microbubble destruction (UTMD) technology is a new drug and gene delivery strategy. This study investigates novel ultrasound (US) sensitive siRNA-loaded nanobubbles (siRNA-NBs) to explore the relationship between PDLIM5 mediated autophagy and drug resistance developme...

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Detalles Bibliográficos
Autores principales:	Zhang, Yao, Lv, Wenhao, Li, Hui, Dong, Tiantian, Wu, Hao, Su, Chunhong, Shu, Hong, Nie, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509593/ https://www.ncbi.nlm.nih.gov/pubmed/36154921 http://dx.doi.org/10.1186/s12935-022-02718-4

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