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Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose
BACKGROUND: 5-hydroxytryptophan (5-HTP), the direct biosynthetic precursor of the neurotransmitter 5-hydroxytryptamine, has been shown to have unique efficacy in the treatment of a variety of disorders, including depression, insomnia, and chronic headaches, and is one of the most commercially valuab...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509612/ https://www.ncbi.nlm.nih.gov/pubmed/36153615 http://dx.doi.org/10.1186/s12934-022-01920-3 |