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Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose

BACKGROUND: 5-hydroxytryptophan (5-HTP), the direct biosynthetic precursor of the neurotransmitter 5-hydroxytryptamine, has been shown to have unique efficacy in the treatment of a variety of disorders, including depression, insomnia, and chronic headaches, and is one of the most commercially valuab...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Yu, Zichen, Wang, Jinduo, Yu, Yifa, Li, Lanxiao, Sun, Pengjie, Fan, Xiaoguang, Xu, Qingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509612/
https://www.ncbi.nlm.nih.gov/pubmed/36153615
http://dx.doi.org/10.1186/s12934-022-01920-3