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BMSC-derived exosomal miR-27a-3p and miR-196b-5p regulate bone remodeling in ovariectomized rats

BACKGROUND: In the bone marrow microenvironment of postmenopausal osteoporosis (PMOP), bone marrow mesenchymal stem cell (BMSC)-derived exosomal miRNAs play an important role in bone formation and bone resorption, although the pathogenesis has yet to be clarified. METHODS: BMSC-derived exosomes from...

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Detalles Bibliográficos
Autores principales: Lai, Guohua, Zhao, Renli, Zhuang, Weida, Hou, Zuoxu, Yang, Zefeng, He, Peipei, Wu, Jiachang, Sang, Hongxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509671/
https://www.ncbi.nlm.nih.gov/pubmed/36168439
http://dx.doi.org/10.7717/peerj.13744