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Chemical shift assignments of the C-terminal domain of CaBP1 bound to the IQ-motif of voltage-gated Ca(2+) channel (Ca(V)1.2)
The neuronal L-type voltage-gated Ca(2+) channel (Ca(V)1.2) interacts with Ca(2+) binding protein 1 (CaBP1), that promotes Ca(2+)-induced channel activity. The binding of CaBP1 to the IQ-motif in Ca(V)1.2 (residues 1644–1665) blocks the binding of calmodulin and prevents Ca(2+)-dependent inactivatio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510106/ https://www.ncbi.nlm.nih.gov/pubmed/36064846 http://dx.doi.org/10.1007/s12104-022-10108-0 |