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Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides
To deliver useful biological payloads into the cytosolic space of cells, cell-penetrating peptides have to cross biological membranes. The molecular features that control or enhance this activity remain unclear. Herein, a dimeric template of the arginine-rich HIV TAT CPP was used to establish the ef...
Autores principales: | Allen, Jason, Pellois, Jean-Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510126/ https://www.ncbi.nlm.nih.gov/pubmed/36156072 http://dx.doi.org/10.1038/s41598-022-20425-y |
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