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miR-329– and miR-495–mediated Prr7 down-regulation is required for homeostatic synaptic depression in rat hippocampal neurons

Homeostatic synaptic depression (HSD) in excitatory neurons is a cell-autonomous mechanism which protects excitatory neurons from over-excitation as a consequence of chronic increases in network activity. In this process, excitatory synapses are weakened and eventually eliminated, as evidenced by a...

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Detalles Bibliográficos
Autores principales: Inouye, Michiko O, Colameo, David, Ammann, Irina, Winterer, Jochen, Schratt, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510147/
https://www.ncbi.nlm.nih.gov/pubmed/36150742
http://dx.doi.org/10.26508/lsa.202201520