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Mechanism of action of DSP-7888 (adegramotide/nelatimotide) Emulsion, a peptide-based therapeutic cancer vaccine with the potential to turn up the heat on non-immunoreactive tumors

BACKGROUND: Wilms’ tumor 1 (WT1) is highly expressed in various solid tumors and hematologic malignancies. DSP-7888 (adegramotide/nelatimotide) Emulsion is an investigational therapeutic cancer vaccine comprising three synthetic epitopes derived from WT1. We evaluated the mechanism of action of DSP-...

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Detalles Bibliográficos
Autores principales: Suginobe, Natsuko, Nakamura, Megumi, Takanashi, Yosuke, Ban, Hitoshi, Gotoh, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510518/
https://www.ncbi.nlm.nih.gov/pubmed/36138335
http://dx.doi.org/10.1007/s12094-022-02946-0