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Mechanism of action of DSP-7888 (adegramotide/nelatimotide) Emulsion, a peptide-based therapeutic cancer vaccine with the potential to turn up the heat on non-immunoreactive tumors
BACKGROUND: Wilms’ tumor 1 (WT1) is highly expressed in various solid tumors and hematologic malignancies. DSP-7888 (adegramotide/nelatimotide) Emulsion is an investigational therapeutic cancer vaccine comprising three synthetic epitopes derived from WT1. We evaluated the mechanism of action of DSP-...
Autores principales: | Suginobe, Natsuko, Nakamura, Megumi, Takanashi, Yosuke, Ban, Hitoshi, Gotoh, Masashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510518/ https://www.ncbi.nlm.nih.gov/pubmed/36138335 http://dx.doi.org/10.1007/s12094-022-02946-0 |
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