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Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function
INTRODUCTION: We previously showed that attenuated glucocorticoid receptor (GR) function in mice (GR(dim/dim)) aggravates systemic hypotension and impairs organ function during endotoxic shock. Hemorrhagic shock (HS) causes impaired organ perfusion, which leads to tissue hypoxia and inflammation wit...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510589/ https://www.ncbi.nlm.nih.gov/pubmed/36172380 http://dx.doi.org/10.3389/fimmu.2022.980707 |