Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function

INTRODUCTION: We previously showed that attenuated glucocorticoid receptor (GR) function in mice (GR(dim/dim)) aggravates systemic hypotension and impairs organ function during endotoxic shock. Hemorrhagic shock (HS) causes impaired organ perfusion, which leads to tissue hypoxia and inflammation wit...

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Detalles Bibliográficos
Autores principales: Wepler, Martin, Preuss, Jonathan M., Tilp, Cornelia, Keck, Martina, Blender, Jochen, Wachter, Ulrich, Merz, Tamara, Vogt, Josef, Kress, Sandra, Gröger, Michael, Hoffmann, Andrea, Fink, Marina, Calzia, Enrico, Burret, Ute, Radermacher, Peter, Tuckermann, Jan P., Vettorazzi, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510589/
https://www.ncbi.nlm.nih.gov/pubmed/36172380
http://dx.doi.org/10.3389/fimmu.2022.980707

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