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Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients

Paroxetine is one of the most potent selective serotonin reuptake inhibitors (SSRIs) approved for treating depression, panic disorder, and obsessive-compulsive disorder. There is evidence linking genetic polymorphisms and nonlinear metabolism to the Paroxetine’s pharmacokinetic (PK) variability. The...

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Detalles Bibliográficos
Autores principales: Li, Xiao-lin, Huang, Shan-qing, Xiao, Tao, Wang, Xi-pei, Kong, Wan, Liu, Shu-jing, Zhang, Zi, Yang, Ye, Huang, Shan-shan, Ni, Xiao-jia, Lu, Hao-yang, Zhang, Ming, Wen, Yu-guan, Shang, De-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510632/
https://www.ncbi.nlm.nih.gov/pubmed/36172189
http://dx.doi.org/10.3389/fphar.2022.966622