Chronic intermittent hypoxia accelerates cardiac dysfunction and cardiac remodeling during cardiac pressure overload in mice and can be alleviated by PHD3 overexpression

Obstructive sleep apnea (OSA) accelerates the progression of chronic heart failure (CHF). OSA is characterized by chronic intermittent hypoxia (CIH), and CIH exposure accelerates cardiac systolic dysfunction and cardiac remodeling in a cardiac afterload stress mouse model. Mechanistic experiments sh...

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Detalles Bibliográficos
Autores principales: Xu, Xuan, Zhen, Peng-Hao, Yu, Fu-Chao, Wang, Tao, Li, Sheng-Nan, Wei, Qin, Tong, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510693/
https://www.ncbi.nlm.nih.gov/pubmed/36172572
http://dx.doi.org/10.3389/fcvm.2022.974345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510693/
https://www.ncbi.nlm.nih.gov/pubmed/36172572
http://dx.doi.org/10.3389/fcvm.2022.974345

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