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Chronic intermittent hypoxia accelerates cardiac dysfunction and cardiac remodeling during cardiac pressure overload in mice and can be alleviated by PHD3 overexpression
Obstructive sleep apnea (OSA) accelerates the progression of chronic heart failure (CHF). OSA is characterized by chronic intermittent hypoxia (CIH), and CIH exposure accelerates cardiac systolic dysfunction and cardiac remodeling in a cardiac afterload stress mouse model. Mechanistic experiments sh...
Autores principales: | Xu, Xuan, Zhen, Peng-Hao, Yu, Fu-Chao, Wang, Tao, Li, Sheng-Nan, Wei, Qin, Tong, Jia-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510693/ https://www.ncbi.nlm.nih.gov/pubmed/36172572 http://dx.doi.org/10.3389/fcvm.2022.974345 |
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