MeCP2 heterochromatin organization is modulated by arginine methylation and serine phosphorylation

Rett syndrome is a human intellectual disability disorder that is associated with mutations in the X-linked MECP2 gene. The epigenetic reader MeCP2 binds to methylated cytosines on the DNA and regulates chromatin organization. We have shown previously that MECP2 Rett syndrome missense mutations are...

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Detalles Bibliográficos
Autores principales: Schmidt, Annika, Frei, Jana, Poetsch, Ansgar, Chittka, Alexandra, Zhang, Hui, Aßmann, Chris, Lehmkuhl, Anne, Bauer, Uta-Maria, Nuber, Ulrike A., Cardoso, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510713/
https://www.ncbi.nlm.nih.gov/pubmed/36172281
http://dx.doi.org/10.3389/fcell.2022.941493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510713/
https://www.ncbi.nlm.nih.gov/pubmed/36172281
http://dx.doi.org/10.3389/fcell.2022.941493

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