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MeCP2 heterochromatin organization is modulated by arginine methylation and serine phosphorylation
Rett syndrome is a human intellectual disability disorder that is associated with mutations in the X-linked MECP2 gene. The epigenetic reader MeCP2 binds to methylated cytosines on the DNA and regulates chromatin organization. We have shown previously that MECP2 Rett syndrome missense mutations are...
Autores principales: | Schmidt, Annika, Frei, Jana, Poetsch, Ansgar, Chittka, Alexandra, Zhang, Hui, Aßmann, Chris, Lehmkuhl, Anne, Bauer, Uta-Maria, Nuber, Ulrike A., Cardoso, M. Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510713/ https://www.ncbi.nlm.nih.gov/pubmed/36172281 http://dx.doi.org/10.3389/fcell.2022.941493 |
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