Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component

The genome of pathogenic Leptospira interrogans serovars (Copenhageni and Lai) are predicted to have CRISPR-Cas of subtypes I-B and I-C. Cas2, one of the core Cas proteins, has a crucial role in adaptive defense against foreign nucleic acids. However, subtype I-C lacks the CRISPR element at its loci...

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Detalles Bibliográficos
Autores principales: Anand, Vineet, Prabhakaran, Harshini Sheeja, Gogoi, Prerana, Kanaujia, Shankar Prasad, Kumar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510766/
https://www.ncbi.nlm.nih.gov/pubmed/36172044
http://dx.doi.org/10.3389/fmolb.2022.988569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510766/
https://www.ncbi.nlm.nih.gov/pubmed/36172044
http://dx.doi.org/10.3389/fmolb.2022.988569

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