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Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component
The genome of pathogenic Leptospira interrogans serovars (Copenhageni and Lai) are predicted to have CRISPR-Cas of subtypes I-B and I-C. Cas2, one of the core Cas proteins, has a crucial role in adaptive defense against foreign nucleic acids. However, subtype I-C lacks the CRISPR element at its loci...
Autores principales: | Anand, Vineet, Prabhakaran, Harshini Sheeja, Gogoi, Prerana, Kanaujia, Shankar Prasad, Kumar, Manish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510766/ https://www.ncbi.nlm.nih.gov/pubmed/36172044 http://dx.doi.org/10.3389/fmolb.2022.988569 |
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