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Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein

Increased neutrophils and elevated level of circulating calprotectin are hallmarks of severe COVID-19 and they contribute to the dysregulated immune responses and cytokine storm in susceptible patients. However, the precise mechanism controlling calprotectin production during SARS-CoV-2 infection re...

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Detalles Bibliográficos
Autores principales: Loh, Jia Tong, Teo, Joey Kay Hui, Lam, Kong-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510782/
https://www.ncbi.nlm.nih.gov/pubmed/36172386
http://dx.doi.org/10.3389/fimmu.2022.996637