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New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors

Dipeptidyl peptidase 8 (DPP8) and 9 (DPP9) are widely expressed in mammals including humans, mainly locate in the cytoplasm. The DPP8 and DPP9 (DPP8/9) belong to serine proteolytic enzymes, they can recognize and cleave N-terminal dipeptides of specific substrates if proline is at the penultimate po...

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Detalles Bibliográficos
Autores principales: Cui, Chenkai, Tian, Xuefei, Wei, Linting, Wang, Yinhong, Wang, Kexin, Fu, Rongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510841/
https://www.ncbi.nlm.nih.gov/pubmed/36172198
http://dx.doi.org/10.3389/fphar.2022.1002871