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Epithelial Cells in 2D and 3D Cultures Exhibit Large Differences in Higher-order Genomic Interactions

Recent studies have characterized the genomic structures of many eukaryotic cells, often focusing on their relation to gene expression. However, these studies have largely investigated cells grown in 2D cultures, although the transcriptomes of 3D-cultured cells are generally closer to their in vivo...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Sun, Qiu, Wang, Qi, Hu, Chuansheng, Chen, Xuecheng, Li, Hua, Czajkowsky, Daniel M., Shao, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510857/
https://www.ncbi.nlm.nih.gov/pubmed/33631432
http://dx.doi.org/10.1016/j.gpb.2020.06.017