Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells

Human N-acetylgalactosamine-α2,6-sialyltransferase (hST6GalNAc I) is the major enzyme involved in the biosynthesis of sialyl-Tn antigen (sTn), which is known to be expressed in more than 80% of human carcinomas and correlated with poor prognosis in cancer patients. Athough high expression of hST6Gal...

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Detalles Bibliográficos
Autores principales: An, So-Young, Kim, Kyoung-Sook, Cho, Jong-Hyun, Kim, Hee-Do, Kim, Cheorl-Ho, Lee, Young-Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510914/
https://www.ncbi.nlm.nih.gov/pubmed/36172045
http://dx.doi.org/10.3389/fmolb.2022.985648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510914/
https://www.ncbi.nlm.nih.gov/pubmed/36172045
http://dx.doi.org/10.3389/fmolb.2022.985648

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