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Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells
Human N-acetylgalactosamine-α2,6-sialyltransferase (hST6GalNAc I) is the major enzyme involved in the biosynthesis of sialyl-Tn antigen (sTn), which is known to be expressed in more than 80% of human carcinomas and correlated with poor prognosis in cancer patients. Athough high expression of hST6Gal...
Autores principales: | An, So-Young, Kim, Kyoung-Sook, Cho, Jong-Hyun, Kim, Hee-Do, Kim, Cheorl-Ho, Lee, Young-Choon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510914/ https://www.ncbi.nlm.nih.gov/pubmed/36172045 http://dx.doi.org/10.3389/fmolb.2022.985648 |
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