SIRT6 overexpression retards renal interstitial fibrosis through targeting HIPK2 in chronic kidney disease

Introduction: Renal interstitial fibrosis is a common pathophysiological change in the chronic kidney disease (CKD). Nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin 6 (SIRT6) is demonstrated to protect against kidney injury. Vitamin B3 is the mostly used form of NAD precursors....

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Detalles Bibliográficos
Autores principales: Li, Xiaoxue, Li, Wenxin, Zhang, Zhengzhipeng, Wang, Weidong, Huang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510922/
https://www.ncbi.nlm.nih.gov/pubmed/36172184
http://dx.doi.org/10.3389/fphar.2022.1007168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510922/
https://www.ncbi.nlm.nih.gov/pubmed/36172184
http://dx.doi.org/10.3389/fphar.2022.1007168

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