ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis

Beta-cell destruction in type 1 diabetes (T1D) results from the combined effect of inflammation and recurrent autoimmunity. Accumulating evidence suggests the engagement of cellular stress during the initial stage of the disease, preceding destruction and triggering immune cell infiltration. While t...

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Detalles Bibliográficos
Autores principales: Vig, Saurabh, Lambooij, Joost M., Dekkers, Mette C., Otto, Frank, Carlotti, Françoise, Guigas, Bruno, Zaldumbide, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511040/
https://www.ncbi.nlm.nih.gov/pubmed/36171907
http://dx.doi.org/10.3389/fendo.2022.991632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511040/
https://www.ncbi.nlm.nih.gov/pubmed/36171907
http://dx.doi.org/10.3389/fendo.2022.991632

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