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Further investigation of blockade effects and binding affinities of selected natural compounds to immune checkpoint PD-1/PD-L1

The breakthrough in the discovery of immune checkpoint PD-1/PD-L1 inhibitors, such as the series of Bristol Myers Squibb synthetic compounds, boosted the research of small molecules with blockade effects on the interaction of PD-1/PD-L1. However, the search for natural products derived PD-1/PD-L1 in...

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Detalles Bibliográficos
Autores principales: Li, Huifang, Seeram, Navindra P., Liu, Chang, Ma, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511049/
https://www.ncbi.nlm.nih.gov/pubmed/36172167
http://dx.doi.org/10.3389/fonc.2022.995461