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Further investigation of blockade effects and binding affinities of selected natural compounds to immune checkpoint PD-1/PD-L1
The breakthrough in the discovery of immune checkpoint PD-1/PD-L1 inhibitors, such as the series of Bristol Myers Squibb synthetic compounds, boosted the research of small molecules with blockade effects on the interaction of PD-1/PD-L1. However, the search for natural products derived PD-1/PD-L1 in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511049/ https://www.ncbi.nlm.nih.gov/pubmed/36172167 http://dx.doi.org/10.3389/fonc.2022.995461 |