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Thromboelastography and thrombin generation assessments for pediatric severe hemophilia A patients are highly variable and not predictive of clinical phenotypes

BACKGROUND: Severe hemophilia A (SHA) patients vary in severity of bleeding, arthropathy, and requirements for replacement factor VIII (FVIII). Baseline hemostatic activity assays using calibrated automated thrombography (CAT) and thromboelastography (TEG) may offer insights into the physiological b...

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Detalles Bibliográficos
Autores principales: Mathews, Natalie, Pluthero, Fred G., Rand, Margaret L., Stain, Ann Marie, Carcao, Manuel, Blanchette, Victor S., Kahr, Walter H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511091/
https://www.ncbi.nlm.nih.gov/pubmed/36186102
http://dx.doi.org/10.1002/rth2.12800