Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet

Obesity is characterized by lipid accumulation in distinct organs. Presently, fenofibrate is a commonly used triglyceride-lowering drug. This study is designed to investigate whether long-term fenofibrate intervention can attenuate lipid accumulation in ob/ob mouse, a typical model of obesity. Our d...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Jia, Xiu-Bin, Liu, Yun-Chao, Yu, Wen-Qian, Si, Yan-Hong, Guo, Shou-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511108/
https://www.ncbi.nlm.nih.gov/pubmed/36172518
http://dx.doi.org/10.3389/fnut.2022.971581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511108/
https://www.ncbi.nlm.nih.gov/pubmed/36172518
http://dx.doi.org/10.3389/fnut.2022.971581

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