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Association between EGFR gene mutant protein expression and T790M mutation after first-generation EGFR-TKI treatment resistance: a retrospective, single-arm clinical study

BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is an important treatment for lung adenocarcinoma patients with EGFR gene mutations. The purpose of this study was to review the efficacy of first-generation EGFR-TKIs and the incidence of T790M after first-generation...

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Detalles Bibliográficos
Autores principales: Zhang, Yiruo, Huang, Xin, Niu, Ruiqi, Li, Chenghui, Pang, Jingdan, Liu, Pingping, Adachi, Hiroyuki, Kawase, Akikazu, Yamaguchi, Fumihiro, Du, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511196/
https://www.ncbi.nlm.nih.gov/pubmed/36172116
http://dx.doi.org/10.21037/atm-22-3850