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Association between EGFR gene mutant protein expression and T790M mutation after first-generation EGFR-TKI treatment resistance: a retrospective, single-arm clinical study
BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is an important treatment for lung adenocarcinoma patients with EGFR gene mutations. The purpose of this study was to review the efficacy of first-generation EGFR-TKIs and the incidence of T790M after first-generation...
Autores principales: | Zhang, Yiruo, Huang, Xin, Niu, Ruiqi, Li, Chenghui, Pang, Jingdan, Liu, Pingping, Adachi, Hiroyuki, Kawase, Akikazu, Yamaguchi, Fumihiro, Du, Yingying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511196/ https://www.ncbi.nlm.nih.gov/pubmed/36172116 http://dx.doi.org/10.21037/atm-22-3850 |
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