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Tumorous expression of NAC1 restrains antitumor immunity through the LDHA-mediated immune evasion

BACKGROUND: T cell-mediated antitumor immunity has a vital role in cancer prevention and treatment; however, the immune-suppressive tumor microenvironment (TME) constitutes a significant contributor to immune evasion that weakens antitumor immunity. Here, we explore the relationship between nucleus...

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Detalles Bibliográficos
Autores principales: Ren, Yijie, Kumar, Anil, Das, Jugal K, Peng, Hao-Yun, Wang, Liqing, Balllard, Darby, Xiong, Xiaofang, Ren, Xingcong, Zhang, Yi, Yang, Jin-Ming, Song, Jianxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511653/
https://www.ncbi.nlm.nih.gov/pubmed/36150745
http://dx.doi.org/10.1136/jitc-2022-004856