Mitigating the prevalence and function of myeloid-derived suppressor cells by redirecting myeloid differentiation using a novel immune modulator

BACKGROUND: Immune suppression is common in neoplasia and a major driver is tumor-induced myeloid dysfunction. Yet, overcoming such myeloid cell defects remains an untapped strategy to reverse suppression and improve host defense. Exposure of bone marrow progenitors to heightened levels of myeloid g...

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Detalles Bibliográficos
Autores principales: Oliver, Liliana, Alvarez, Rydell, Diaz, Raquel, Valdés, Anet, Colligan, Sean H, Nemeth, Michael J, Twum, Danielle Y F, Fernández, Audry, Fernández-Medina, Olivia, Carlson, Louise M, Yu, Han, Eng, Kevin H, Hensen, Mary L, Rábade-Chediak, Maura L, Fernández, Luis Enrique, Lee, Kelvin P, Perez, Leslie, Muhitch, Jason B, Mesa, Circe, Abrams, Scott I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511656/
https://www.ncbi.nlm.nih.gov/pubmed/36150744
http://dx.doi.org/10.1136/jitc-2022-004710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511656/
https://www.ncbi.nlm.nih.gov/pubmed/36150744
http://dx.doi.org/10.1136/jitc-2022-004710

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