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Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy

BACKGROUND AND AIMS: The role of inflammatory immune responses in colorectal cancer (CRC) development and response to therapy is a matter of intense debate. While inflammation is a known driver of CRC, inflammatory immune infiltrates are a positive prognostic factor in CRC and predispose to response...

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Detalles Bibliográficos
Autores principales: Krieg, Carsten, Weber, Lukas M, Fosso, Bruno, Marzano, Marinella, Hardiman, Gary, Olcina, Monica M, Domingo, Enric, El Aidy, Sahar, Mallah, Khalil, Robinson, Mark D, Guglietta, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511657/
https://www.ncbi.nlm.nih.gov/pubmed/36137652
http://dx.doi.org/10.1136/jitc-2022-004717