A Zn(2+)-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels

The chloride intracellular channel (CLIC) protein family displays the unique feature of altering its structure from a soluble form to a membrane-bound chloride channel. CLIC1, a member of this family, is found in the cytoplasm or in internal and plasma membranes, with membrane relocalisation linked...

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Detalles Bibliográficos
Autores principales: Varela, Lorena, Hendry, Alex C., Cassar, Joseph, Martin-Escolano, Ruben, Cantoni, Diego, Ossa, Felipe, Edwards, John C., Abdul-Salam, Vahitha, Ortega-Roldan, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511705/
https://www.ncbi.nlm.nih.gov/pubmed/35833483
http://dx.doi.org/10.1242/jcs.259704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511705/
https://www.ncbi.nlm.nih.gov/pubmed/35833483
http://dx.doi.org/10.1242/jcs.259704

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