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A Zn(2+)-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels
The chloride intracellular channel (CLIC) protein family displays the unique feature of altering its structure from a soluble form to a membrane-bound chloride channel. CLIC1, a member of this family, is found in the cytoplasm or in internal and plasma membranes, with membrane relocalisation linked...
Autores principales: | Varela, Lorena, Hendry, Alex C., Cassar, Joseph, Martin-Escolano, Ruben, Cantoni, Diego, Ossa, Felipe, Edwards, John C., Abdul-Salam, Vahitha, Ortega-Roldan, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511705/ https://www.ncbi.nlm.nih.gov/pubmed/35833483 http://dx.doi.org/10.1242/jcs.259704 |
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