Base excision repair accessory factors in senescence avoidance and resistance to treatments

Cancer cells, in which the RAS and PI3K pathways are activated, produce high levels of reactive oxygen species (ROS), which cause oxidative DNA damage and ultimately cellular senescence. This process has been documented in tissue culture, mouse models, and human pre-cancerous lesions. In this contex...

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Detalles Bibliográficos
Autores principales: Vickridge, Elise, Faraco, Camila C. F., Nepveu, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511810/
https://www.ncbi.nlm.nih.gov/pubmed/36176767
http://dx.doi.org/10.20517/cdr.2022.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511810/
https://www.ncbi.nlm.nih.gov/pubmed/36176767
http://dx.doi.org/10.20517/cdr.2022.36

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